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Efficacy of antiresorptive agents bisphosphonates and denosumab in mitigating hypercalcemia and bone loss in primary hyperparathyroidism: A systematic review and meta-analysis

PURPOSE: Primary hyperparathyroidism (PHPT) is characterized by increased bone remodeling and hypercalcemia. Parathyroidectomy (PTX), the current standard of care, is recommended in all symptomatic and some groups of asymptomatic patients. Anti-resorptive therapies (bisphosphonates and denosumab) ha...

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Detalles Bibliográficos
Autores principales: Rajput, Swati, Dutta, Aditya, Rajender, Singh, Mithal, Ambrish, Chattopadhyay, Naibedya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931892/
https://www.ncbi.nlm.nih.gov/pubmed/36817591
http://dx.doi.org/10.3389/fendo.2023.1098841