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Anti-malarial artesunate ameliorates atherosclerosis by modulating arterial inflammatory responses via inhibiting the NF-κB–NLRP3 inflammasome pathway

Introduction: Chronic inflammation plays a critical role in the pathogenesis of atherosclerosis (AS), and involves a complex interplay between blood components, macrophages, and arterial wall. Therefore, it is valuable in the development of targeted therapies to treat AS. Methods: AS rat model was i...

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Detalles Bibliográficos
Autores principales: Cen, Yanyan, Xiong, Yalan, Qin, Rongxin, Tao, Hui, Yang, Qunfang, Pan, Xichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931906/
https://www.ncbi.nlm.nih.gov/pubmed/36817159
http://dx.doi.org/10.3389/fphar.2023.1123700