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Chronic treatment with baicalein alleviates behavioural disorders and improves cerebral blood flow via reverting metabolic abnormalities in a J20 transgenic mouse model of Alzheimer's disease

Baicalein (BE) has both antioxidant and anti-inflammatory effects. It has also been reported able to improve cerebral blood circulation in brain ischemic injury. However, its chronic efficacy and metabolomics in Alzheimer's disease (AD) remain unknown. In this study, BE at 80 mg/kg was administ...

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Detalles Bibliográficos
Autores principales:	Zhang, Li, Wong, Ling Rong, Wong, Peiyan, Shen, Wanxiang, Yang, Shili, Huang, Lizhen, Lim, Yun-An, Ho, Paul Chi-Lui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Full Length Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931920/ https://www.ncbi.nlm.nih.gov/pubmed/36817510 http://dx.doi.org/10.1016/j.bbih.2023.100599

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