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VPS35 promotes cell proliferation via EGFR recycling and enhances EGFR inhibitors response in gastric cancer

BACKGROUND: Vacuolar protein sorting-associated protein 35 (VPS35) is a core component of the retromer complex which mediates intracellular protein transport. It is well known that dysfunctional VPS35 functions in the accumulation of pathogenic proteins. In our previous study, VPS35 was found to be...

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Detalles Bibliográficos
Autores principales: Yu, Junxian, Feng, Haoran, Sang, Qingqing, Li, Fangyuan, Chen, Mengdi, Yu, Beiqin, Xu, Zhuoqing, Pan, Tao, Wu, Xiongyan, Hou, Junyi, Zhu, Zhenggang, Yan, Chao, Su, Liping, Li, Jianfang, Liu, Bingya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931929/
https://www.ncbi.nlm.nih.gov/pubmed/36738481
http://dx.doi.org/10.1016/j.ebiom.2023.104451