DNALI1 deficiency causes male infertility with severe asthenozoospermia in humans and mice by disrupting the assembly of the flagellar inner dynein arms and fibrous sheath

The axonemal dynein arms (outer (ODA) and inner dynein arms (IDAs)) are multiprotein structures organized by light, intermediate, light intermediate (LIC), and heavy chain proteins. They hydrolyze ATP to promote ciliary and flagellar movement. Till now, a variety of dynein protein deficiencies have...

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Detalles Bibliográficos
Autores principales: Wu, Huan, Liu, Yiyuan, Li, Yuqian, Li, Kuokuo, Xu, Chuan, Gao, Yang, Lv, Mingrong, Guo, Rui, Xu, Yuping, Zhou, Ping, Wei, Zhaolian, Hua, Rong, He, Xiaojin, Cao, Yunxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932082/
https://www.ncbi.nlm.nih.gov/pubmed/36792588
http://dx.doi.org/10.1038/s41419-023-05653-y

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