Polo-like kinase 1 (PLK1) O-GlcNAcylation is essential for dividing mammalian cells and inhibits uterine carcinoma

The O-linked β-N-acetylglucosamine (O-GlcNAc) transferase (OGT) mediates intracellular O-GlcNAcylation modification. O-GlcNAcylation occurs on Ser/Thr residues and is important for numerous physiological processes. OGT is essential for dividing mammalian cells and is involved in many human diseases;...

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Detalles Bibliográficos
Autores principales: Yan, Sheng, Peng, Bin, Kan, Shifeng, Shao, Guangcan, Xiahou, Zhikai, Tang, Xiangyan, Chen, Yong-Xiang, Dong, Meng-Qiu, Liu, Xiao, Xu, Xingzhi, Li, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932112/
https://www.ncbi.nlm.nih.gov/pubmed/36626982
http://dx.doi.org/10.1016/j.jbc.2023.102887

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