Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia

ZBTB7A belongs to a small family of transcription factors having three members in humans (7A, 7B, and 7C). They share a BTB/POZ protein interaction domain at the amino end and a zinc-finger DNA-binding domain at the carboxyl end. They control the transcription of a wide range of genes, having varied...

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Detalles Bibliográficos
Autores principales: Ren, Ren, Horton, John R., Chen, Qin, Yang, Jie, Liu, Bin, Huang, Yun, Blumenthal, Robert M., Zhang, Xing, Cheng, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932118/
https://www.ncbi.nlm.nih.gov/pubmed/36626981
http://dx.doi.org/10.1016/j.jbc.2023.102885

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