Augmenting hematoma-scavenging capacity of innate immune cells by CDNF reduces brain injury and promotes functional recovery after intracerebral hemorrhage

During intracerebral hemorrhage (ICH), hematoma formation at the site of blood vessel damage results in local mechanical injury. Subsequently, erythrocytes lyse to release hemoglobin and heme, which act as neurotoxins and induce inflammation and secondary brain injury, resulting in severe neurologic...

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Detalles Bibliográficos
Autores principales: Tseng, Kuan-Yin, Stratoulias, Vassilis, Hu, Wei-Fen, Wu, Jui-Sheng, Wang, Vicki, Chen, Yuan-Hao, Seelbach, Anna, Huttunen, Henri J., Kulesskaya, Natalia, Pang, Cheng-Yoong, Chou, Jian-Liang, Lindahl, Maria, Saarma, Mart, Huang, Li-Chuan, Airavaara, Mikko, Liew, Hock-Kean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932138/
https://www.ncbi.nlm.nih.gov/pubmed/36792604
http://dx.doi.org/10.1038/s41419-022-05520-2

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