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Efficient breast cancer mammograms diagnosis using three deep neural networks and term variance

Breast cancer (BC) is spreading more and more every day. Therefore, a patient's life can be saved by its early discovery. Mammography is frequently used to diagnose BC. The classification of mammography region of interest (ROI) patches (i.e., normal, malignant, or benign) is the most crucial ph...

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Autores principales: Elkorany, Ahmed S., Elsharkawy, Zeinab F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932150/
https://www.ncbi.nlm.nih.gov/pubmed/36792720
http://dx.doi.org/10.1038/s41598-023-29875-4
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author Elkorany, Ahmed S.
Elsharkawy, Zeinab F.
author_facet Elkorany, Ahmed S.
Elsharkawy, Zeinab F.
author_sort Elkorany, Ahmed S.
collection PubMed
description Breast cancer (BC) is spreading more and more every day. Therefore, a patient's life can be saved by its early discovery. Mammography is frequently used to diagnose BC. The classification of mammography region of interest (ROI) patches (i.e., normal, malignant, or benign) is the most crucial phase in this process since it helps medical professionals to identify BC. In this paper, a hybrid technique that carries out a quick and precise classification that is appropriate for the BC diagnosis system is proposed and tested. Three different Deep Learning (DL) Convolution Neural Network (CNN) models—namely, Inception-V3, ResNet50, and AlexNet—are used in the current study as feature extractors. To extract useful features from each CNN model, our suggested method uses the Term Variance (TV) feature selection algorithm. The TV-selected features from each CNN model are combined and a further selection is performed to obtain the most useful features which are sent later to the multiclass support vector machine (MSVM) classifier. The Mammographic Image Analysis Society (MIAS) image database was used to test the effectiveness of the suggested method for classification. The mammogram's ROI is retrieved, and image patches are assigned to it. Based on the results of testing several TV feature subsets, the 600-feature subset with the highest classification performance was discovered. Higher classification accuracy (CA) is attained when compared to previously published work. The average CA for 70% of training is 97.81%, for 80% of training, it is 98%, and for 90% of training, it reaches its optimal value. Finally, the ablation analysis is performed to emphasize the role of the proposed network’s key parameters.
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spelling pubmed-99321502023-02-17 Efficient breast cancer mammograms diagnosis using three deep neural networks and term variance Elkorany, Ahmed S. Elsharkawy, Zeinab F. Sci Rep Article Breast cancer (BC) is spreading more and more every day. Therefore, a patient's life can be saved by its early discovery. Mammography is frequently used to diagnose BC. The classification of mammography region of interest (ROI) patches (i.e., normal, malignant, or benign) is the most crucial phase in this process since it helps medical professionals to identify BC. In this paper, a hybrid technique that carries out a quick and precise classification that is appropriate for the BC diagnosis system is proposed and tested. Three different Deep Learning (DL) Convolution Neural Network (CNN) models—namely, Inception-V3, ResNet50, and AlexNet—are used in the current study as feature extractors. To extract useful features from each CNN model, our suggested method uses the Term Variance (TV) feature selection algorithm. The TV-selected features from each CNN model are combined and a further selection is performed to obtain the most useful features which are sent later to the multiclass support vector machine (MSVM) classifier. The Mammographic Image Analysis Society (MIAS) image database was used to test the effectiveness of the suggested method for classification. The mammogram's ROI is retrieved, and image patches are assigned to it. Based on the results of testing several TV feature subsets, the 600-feature subset with the highest classification performance was discovered. Higher classification accuracy (CA) is attained when compared to previously published work. The average CA for 70% of training is 97.81%, for 80% of training, it is 98%, and for 90% of training, it reaches its optimal value. Finally, the ablation analysis is performed to emphasize the role of the proposed network’s key parameters. Nature Publishing Group UK 2023-02-15 /pmc/articles/PMC9932150/ /pubmed/36792720 http://dx.doi.org/10.1038/s41598-023-29875-4 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Elkorany, Ahmed S.
Elsharkawy, Zeinab F.
Efficient breast cancer mammograms diagnosis using three deep neural networks and term variance
title Efficient breast cancer mammograms diagnosis using three deep neural networks and term variance
title_full Efficient breast cancer mammograms diagnosis using three deep neural networks and term variance
title_fullStr Efficient breast cancer mammograms diagnosis using three deep neural networks and term variance
title_full_unstemmed Efficient breast cancer mammograms diagnosis using three deep neural networks and term variance
title_short Efficient breast cancer mammograms diagnosis using three deep neural networks and term variance
title_sort efficient breast cancer mammograms diagnosis using three deep neural networks and term variance
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932150/
https://www.ncbi.nlm.nih.gov/pubmed/36792720
http://dx.doi.org/10.1038/s41598-023-29875-4
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