Harnessing the reverse cholesterol transport pathway to favor differentiation of monocyte-derived APCs and antitumor responses

Lipid and cholesterol metabolism play a crucial role in tumor cell behavior and in shaping the tumor microenvironment. In particular, enzymatic and non-enzymatic cholesterol metabolism, and derived metabolites control dendritic cell (DC) functions, ultimately impacting tumor antigen presentation wit...

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Detalles Bibliográficos
Autores principales: Raccosta, Laura, Marinozzi, Maura, Costantini, Susan, Maggioni, Daniela, Ferreira, Lorena Maria, Corna, Gianfranca, Zordan, Paola, Sorice, Angela, Farinello, Diego, Bianchessi, Silvia, Riba, Michela, Lazarevic, Dejan, Provero, Paolo, Mack, Matthias, Bondanza, Attilio, Nalvarte, Ivan, Gustafsson, J-A, Ranzani, Valeria, De Sanctis, Francesco, Ugel, Stefano, Baron, Silvère, Lobaccaro, Jean-Marc A., Pontini, Lorenzo, Pacciarini, Manuela, Traversari, Catia, Pagani, Massimiliano, Bronte, Vincenzo, Sitia, Giovanni, Antonson, Per, Brendolan, Andrea, Budillon, Alfredo, Russo, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932151/
https://www.ncbi.nlm.nih.gov/pubmed/36792589
http://dx.doi.org/10.1038/s41419-023-05620-7

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