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Coadaptation fostered by the SLIT2-ROBO1 axis facilitates liver metastasis of pancreatic ductal adenocarcinoma

To explore the mechanism of coadaptation and the potential drivers of pancreatic ductal adenocarcinoma (PDAC) metastasis to the liver, we study key molecules involved in this process and their translational value. Premetastatic niche (PMN) and macrometastatic niche (MMN) formation in a mouse model i...

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Detalles Bibliográficos
Autores principales: Li, Qing, Zhang, Xiao-Xin, Hu, Li-Peng, Ni, Bo, Li, Dong-Xue, Wang, Xu, Jiang, Shu-Heng, Li, Hui, Yang, Min-Wei, Jiang, Yong-Sheng, Xu, Chun-Jie, Zhang, Xue-Li, Zhang, Yan-Li, Huang, Pei-Qi, Yang, Qin, Zhou, Yang, Gu, Jian-ren, Xiao, Gary Gui-Shan, Sun, Yong-wei, Li, Jun, Zhang, Zhi-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932171/
https://www.ncbi.nlm.nih.gov/pubmed/36792623
http://dx.doi.org/10.1038/s41467-023-36521-0