Bovine tuberculosis in India: The need for One Health approach and the way forward

Bovine tuberculosis (bTB) is a chronic granulomatous infectious illness in cattle. The etiological agent of bTB is Mycobacterium bovis. However, other members belonging to the Mycobacterium tuberculosis complex, like M. tuberculosis, M. africanum, M. caprae, M. orygis, and M. microti are known to cause bTB in cattle. There are 303.76 million bovines in India, and it is the largest producer of milk and the second largest producer of meat worldwide. The prevalence of bTB among farm and dairy cattle in India is estimated to be around 7.3%, which makes it a country with one of the largest infected herds in the world. While bTB control programs have had considerable success in reducing the prevalence of the disease in many developed countries, they have yet to be formulated or implemented in India. Bovine TB also has a zoonotic and reverse component, which means that the disease can spread from cattle to human and from human to cattle. In a country like India, which contributes to nearly one-fourth of the global TB burden, the zoonotic aspect must be addressed so that the disease can be curbed. While cattle are the primary reservoir host to bTB, animals like goats, deer, bison, pigs, dogs, badgers, possums, and primates are also susceptible to the disease. This review talks about the burden of bTB in India and the necessity of One Health approach to combat the disease.