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Cross interactions between Apolipoprotein E and amyloid proteins in neurodegenerative diseases

Three common Apolipoprotein E isoforms, ApoE2, ApoE3, and ApoE4, are key regulators of lipid homeostasis, among other functions. Apolipoprotein E can interact with amyloid proteins. The isoforms differ by one or two residues at positions 112 and 158, and possess distinct structural conformations and...

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Detalles Bibliográficos
Autores principales:	Loch, Rolf Antonie, Wang, Hongzhi, Perálvarez-Marín, Alex, Berger, Philipp, Nielsen, Henrietta, Chroni, Angeliki, Luo, Jinghui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Research Network of Computational and Structural Biotechnology 2023
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932299/ https://www.ncbi.nlm.nih.gov/pubmed/36817952 http://dx.doi.org/10.1016/j.csbj.2023.01.022

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