Cargando…

Dysregulated ceramide metabolism in mouse progressive dermatitis resulting from constitutive activation of Jak1

Coordinated lipid metabolism contributes to maintaining skin homeostasis by regulating skin barrier formation, immune reactions, thermogenesis, and perception. Several reports have documented the changes in lipid composition in dermatitis, including in atopic dermatitis (AD); however, the specific m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Iino, Yudai, Naganuma, Tatsuro, Arita, Makoto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932461/ https://www.ncbi.nlm.nih.gov/pubmed/36639058 http://dx.doi.org/10.1016/j.jlr.2023.100329

Ejemplares similares

Targeted Lipidomic and Transcriptomic Analysis Identifies Dysregulated Renal Ceramide Metabolism in a Mouse Model of Diabetic Kidney Disease
por: Sas, Kelli M, et al.
Publicado: (2015)

Efficacy of Heparinoid Cream Containing Pseudo-Ceramide for Remission of Atopic Dermatitis
por: Matsuoka, Megumi, et al.
Publicado: (2021)

The Pathogenic and Therapeutic Implications of Ceramide Abnormalities in Atopic Dermatitis
por: Fujii, Masanori
Publicado: (2021)

Adjustment of Dysregulated Ceramide Metabolism in a Murine Model of Sepsis-Induced Cardiac Dysfunction
por: Chung, Ha-Yeun, et al.
Publicado: (2017)

Dysregulated ceramides metabolism by fatty acid 2-hydroxylase exposes a metabolic vulnerability to target cancer metastasis
por: Zhou, Xuantong, et al.
Publicado: (2022)

Bifunctional DEGS2 has higher hydroxylase activity toward substrates with very-long-chain fatty acids in the production of phytosphingosine ceramides
por: Ota, Ai, et al.
Publicado: (2023)

JAK-STAT Inhibitors in Atopic Dermatitis from Pathogenesis to Clinical Trials Results
por: Szalus, Krzysztof, et al.
Publicado: (2020)

Dysregulation of JAK-STAT pathway in hematological malignancies and JAK inhibitors for clinical application
por: Furqan, Muhammad, et al.
Publicado: (2013)

Derailed Ceramide Metabolism in Atopic Dermatitis (AD): A Causal Starting Point for a Personalized (Basic) Therapy
por: Blaess, Markus, et al.
Publicado: (2019)

Ceramide Induces Human Hepcidin Gene Transcription through JAK/STAT3 Pathway
por: Lu, Sizhao, et al.
Publicado: (2016)

Clinical use of a ceramide-based moisturizer for treating dogs with atopic dermatitis
por: Jung, Ji-young, et al.
Publicado: (2013)

IFN-γ Reduces Epidermal Barrier Function by Affecting Fatty Acid Composition of Ceramide in a Mouse Atopic Dermatitis Model
por: Kanoh, Hiroyuki, et al.
Publicado: (2019)

MAPK and JAK-STAT pathways dysregulation in plasmablastic lymphoma
por: Ramis-Zaldivar, Joan Enric, et al.
Publicado: (2021)

Associations among plasma vitamin C, epidermal ceramide and clinical severity of atopic dermatitis
por: Shin, Jihye, et al.
Publicado: (2016)

Involvement of Ceramide Metabolism in Cerebral Ischemia
por: Ouro, Alberto, et al.
Publicado: (2022)

Ceramide induces MMP-9 expression through JAK2/STAT3 pathway in airway epithelium
por: Xuan, Lingling, et al.
Publicado: (2020)

Efficacy and Safety of JAK1 Inhibitor Abrocitinib in Atopic Dermatitis
por: Iznardo, Helena, et al.
Publicado: (2023)

A New Horizon for Atopic Dermatitis Treatments: JAK Inhibitors
por: Tampa, Mircea, et al.
Publicado: (2023)

Ceramide compensation by ceramide synthases preserves retinal function and structure in a retinal dystrophy mouse model
por: Qian, Xinye, et al.
Publicado: (2023)

In Human and Mouse Spino-Cerebellar Tissue, Ataxin-2 Expansion Affects Ceramide-Sphingomyelin Metabolism
por: Sen, Nesli-Ece, et al.
Publicado: (2019)

Metabolic Dysregulation Contributes to the Progression of Alzheimer’s Disease
por: Yan, Xu, et al.
Publicado: (2020)

Antibacterial activity of ceramide and ceramide analogs against pathogenic Neisseria
por: Becam, Jérôme, et al.
Publicado: (2017)

Brain Ceramide Metabolism in the Control of Energy Balance
por: Cruciani-Guglielmacci, Céline, et al.
Publicado: (2017)

Adipocyte Ceramides—The Nexus of Inflammation and Metabolic Disease
por: Chaurasia, Bhagirath, et al.
Publicado: (2020)

Ceramide Metabolism and Parkinson’s Disease—Therapeutic Targets
por: Custodia, Antía, et al.
Publicado: (2021)

STUDIES ON MOUSE LEUKEMIA : XI. METABOLIC EFFECTS OF HOST CONSTITUTION
por: Victor, Joseph, et al.
Publicado: (1934)

Expression of the JAK/STAT Signaling Pathway in Bullous Pemphigoid and Dermatitis Herpetiformis
por: Juczynska, K., et al.
Publicado: (2017)

JAK–STAT signaling pathway in the pathogenesis of atopic dermatitis: An updated review
por: Huang, I-Hsin, et al.
Publicado: (2022)

Ceramide and ceramide 1-phosphate in health and disease
por: Arana, Lide, et al.
Publicado: (2010)

Intracellular trafficking of ceramide by ceramide transfer protein
por: Hanada, Kentaro
Publicado: (2010)

Efficacy of Pseudo-Ceramide-Containing Steroid Lamellar Cream in Patients with Mild to Moderate Atopic Dermatitis: A Randomized, Double-Blind Study
por: Okoshi, Keita, et al.
Publicado: (2022)

Treating atopic dermatitis: safety, efficacy, and patient acceptability of a ceramide hyaluronic acid emollient foam
por: Pacha, Omar, et al.
Publicado: (2012)

Acceptability and Efficacy of an Emollient Containing Ceramide-Precursor Lipids and Moisturizing Factors for Atopic Dermatitis in Pediatric Patients
por: Hon, Kam Lun, et al.
Publicado: (2013)

Immune Dysregulation and Infectious Complications in MPN Patients Treated With JAK Inhibitors
por: Cattaneo, Daniele, et al.
Publicado: (2021)

Diverse Roles of Ceramide in the Progression and Pathogenesis of Alzheimer’s Disease
por: Chowdhury, Md Riad, et al.
Publicado: (2022)

Ceramide Synthases Expression and Role of Ceramide Synthase-2 in the Lung: Insight from Human Lung Cells and Mouse Models
por: Petrache, Irina, et al.
Publicado: (2013)

Lipid metabolism is dysregulated in a mouse model of diabetes
por: Furse, Samuel
Publicado: (2022)

Reduced ceramide synthase 2 activity causes progressive myoclonic epilepsy
por: Mosbech, Mai-Britt, et al.
Publicado: (2014)

Imaging Mass Spectrometry Visualizes Ceramides and the Pathogenesis of Dorfman-Chanarin Syndrome Due to Ceramide Metabolic Abnormality in the Skin
por: Goto-Inoue, Naoko, et al.
Publicado: (2012)

Lead exposure induces dysregulation of constitutive heterochromatin hallmarks in live cells
por: Sánchez, Oscar F., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_rm29jjeit5o51j93ql55f7ompp