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Transferrin receptor 2 deficiency promotes macrophage polarization and inflammatory arthritis

OBJECTIVE: Rheumatoid arthritis is an inflammatory joint disease in which synovial iron deposition has been described. Transferrin receptor 2 (Tfr2) represents a critical regulator of systemic iron levels. Loss of Tfr2 function in humans and mice results in iron overload. As iron contributes to infl...

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Detalles Bibliográficos
Autores principales:	Ledesma-Colunga, Maria G., Baschant, Ulrike, Weidner, Heike, Alves, Tiago C., Mirtschink, Peter, Hofbauer, Lorenz C., Rauner, Martina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932570/ https://www.ncbi.nlm.nih.gov/pubmed/36746004 http://dx.doi.org/10.1016/j.redox.2023.102616

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