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Intranasal administration of polysulfide prevents neurodegeneration in spinal cord and rescues mice from delayed paraplegia after spinal cord ischemia
BACKGROUND: Delayed paraplegia is a devastating complication of thoracoabdominal aortic surgery. Hydrogen sulfide (H(2)S) was reported to be protective in a mouse model of spinal cord ischemia and the beneficial effect of H(2)S has been attributed to polysulfides. The objective of this study was to...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932672/ https://www.ncbi.nlm.nih.gov/pubmed/36753926 http://dx.doi.org/10.1016/j.redox.2023.102620 |