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Intranasal administration of polysulfide prevents neurodegeneration in spinal cord and rescues mice from delayed paraplegia after spinal cord ischemia

BACKGROUND: Delayed paraplegia is a devastating complication of thoracoabdominal aortic surgery. Hydrogen sulfide (H(2)S) was reported to be protective in a mouse model of spinal cord ischemia and the beneficial effect of H(2)S has been attributed to polysulfides. The objective of this study was to...

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Detalles Bibliográficos
Autores principales:	Kanemaru, Eiki, Miyazaki, Yusuke, Marutani, Eizo, Ezaka, Mariko, Goto, Shunsaku, Ohshima, Etsuo, Bloch, Donald B., Ichinose, Fumito
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Articles from the Special Issue on Recent advances in sulfur biology and chemistry, Edited by: Dr. Peter Nagy
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932672/ https://www.ncbi.nlm.nih.gov/pubmed/36753926 http://dx.doi.org/10.1016/j.redox.2023.102620

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