Cargando…
Histopathological evaluation of Onchocerca volvulus nodules by microscopy and by digital image analysis for the study of macrofilaricidal drug efficacy
BACKGROUND: Novel drugs or drug combinations that kill or permanently sterilize adult Onchocerca volvulus worms would be very helpful for treatment and elimination of onchocerciasis. In absence of a reliable biomarker for viable adult worms, histopathological assessment of worms within onchocercal n...
Autores principales: | Fischer, Kerstin, Dubben, Bettina, Debrah, Linda B., Kuehlwein, Janina M., Ricchiuto, Arcangelo, Debrah, Alexander Y., Hoerauf, Achim, Weil, Gary J., Fischer, Peter U., Klarmann-Schulz, Ute |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932808/ https://www.ncbi.nlm.nih.gov/pubmed/36817770 http://dx.doi.org/10.3389/fmed.2023.1099926 |
Ejemplares similares
-
A qPCR to quantify Wolbachia from few Onchocerca volvulus microfilariae as a surrogate for adult worm histology in clinical trials of antiwolbachial drugs
por: Schlabe, Stefan, et al.
Publicado: (2022) -
Doxycycline Leads to Sterility and Enhanced Killing of Female Onchocerca volvulus Worms in an Area With Persistent Microfilaridermia After Repeated Ivermectin Treatment: A Randomized, Placebo-Controlled, Double-Blind Trial
por: Debrah, Alexander Yaw, et al.
Publicado: (2015) -
Newly acquired Onchocerca volvulus filariae after doxycycline treatment
por: Specht, Sabine, et al.
Publicado: (2009) -
Reductions in microfilaridermia by repeated ivermectin treatment are associated with lower Plasmodium-specific Th17 immune responses in Onchocerca volvulus-infected individuals
por: Arndts, Kathrin, et al.
Publicado: (2015) -
Comparison of Repeated Doses of Ivermectin Versus Ivermectin Plus Albendazole for the Treatment of Onchocerciasis: A Randomized, Open-label, Clinical Trial
por: Batsa Debrah, Linda, et al.
Publicado: (2020)