Cargando…
Occupational Silica Exposure and Pericarditis: An Uncommon Link
Granulomatosis with polyangiitis (GPA) is a multi-system necrotising vasculitis, particularly affecting small vessels. Upper respiratory tracts, lungs and kidneys are common target organs, while cardiac involvement would also be the first and rare manifestation of the disease. In GPA with cardiac in...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932830/ https://www.ncbi.nlm.nih.gov/pubmed/36819347 http://dx.doi.org/10.7759/cureus.33856 |
_version_ | 1784889544105000960 |
---|---|
author | Hein, Aung Willington, Robert Wai, Yin Charan, Mahima |
author_facet | Hein, Aung Willington, Robert Wai, Yin Charan, Mahima |
author_sort | Hein, Aung |
collection | PubMed |
description | Granulomatosis with polyangiitis (GPA) is a multi-system necrotising vasculitis, particularly affecting small vessels. Upper respiratory tracts, lungs and kidneys are common target organs, while cardiac involvement would also be the first and rare manifestation of the disease. In GPA with cardiac involvement, structures such as the pericardium, myocardium, endocardium and conduction system could be involved. In the literature, there are reports of an association between autoimmune diseases and silica exposure. In our case, a 73-year-old sculptor with regular exposure to silica presented with pericarditis and was later diagnosed with granulomatosis with polyangiitis. This report provides additional evidence of an association between silica exposure and autoimmune vasculitis. |
format | Online Article Text |
id | pubmed-9932830 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-99328302023-02-17 Occupational Silica Exposure and Pericarditis: An Uncommon Link Hein, Aung Willington, Robert Wai, Yin Charan, Mahima Cureus Internal Medicine Granulomatosis with polyangiitis (GPA) is a multi-system necrotising vasculitis, particularly affecting small vessels. Upper respiratory tracts, lungs and kidneys are common target organs, while cardiac involvement would also be the first and rare manifestation of the disease. In GPA with cardiac involvement, structures such as the pericardium, myocardium, endocardium and conduction system could be involved. In the literature, there are reports of an association between autoimmune diseases and silica exposure. In our case, a 73-year-old sculptor with regular exposure to silica presented with pericarditis and was later diagnosed with granulomatosis with polyangiitis. This report provides additional evidence of an association between silica exposure and autoimmune vasculitis. Cureus 2023-01-17 /pmc/articles/PMC9932830/ /pubmed/36819347 http://dx.doi.org/10.7759/cureus.33856 Text en Copyright © 2023, Hein et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Internal Medicine Hein, Aung Willington, Robert Wai, Yin Charan, Mahima Occupational Silica Exposure and Pericarditis: An Uncommon Link |
title | Occupational Silica Exposure and Pericarditis: An Uncommon Link |
title_full | Occupational Silica Exposure and Pericarditis: An Uncommon Link |
title_fullStr | Occupational Silica Exposure and Pericarditis: An Uncommon Link |
title_full_unstemmed | Occupational Silica Exposure and Pericarditis: An Uncommon Link |
title_short | Occupational Silica Exposure and Pericarditis: An Uncommon Link |
title_sort | occupational silica exposure and pericarditis: an uncommon link |
topic | Internal Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932830/ https://www.ncbi.nlm.nih.gov/pubmed/36819347 http://dx.doi.org/10.7759/cureus.33856 |
work_keys_str_mv | AT heinaung occupationalsilicaexposureandpericarditisanuncommonlink AT willingtonrobert occupationalsilicaexposureandpericarditisanuncommonlink AT waiyin occupationalsilicaexposureandpericarditisanuncommonlink AT charanmahima occupationalsilicaexposureandpericarditisanuncommonlink |