Reconstruction of Glutathione Metabolism in the Neuronal Model of Rotenone-Induced Neurodegeneration Using Mass Isotopologue Analysis with Hydrophilic Interaction Liquid Chromatography-Zeno High-Resolution Multiple Reaction Monitoring

[Image: see text] Accurate reconstruction of metabolic pathways is an important prerequisite for interpreting metabolomics changes and understanding the diverse biological processes in disease models. A tracer-based metabolomics strategy utilizes stable isotope-labeled precursors to resolve complex...

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Detalles Bibliográficos
Autores principales: Huang, Luojiao, Drouin, Nicolas, Causon, Jason, Wegrzyn, Agnieszka, Castro-Perez, Jose, Fleming, Ronan, Harms, Amy, Hankemeier, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933045/
https://www.ncbi.nlm.nih.gov/pubmed/36735349
http://dx.doi.org/10.1021/acs.analchem.2c04231

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