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Hepatic p63 regulates glucose metabolism by repressing SIRT1
OBJECTIVE: p63 is a transcription factor within the p53 protein family that has key roles in development, differentiation and prevention of senescence, but its metabolic actions remain largely unknown. Herein, we investigated the physiological role of p63 in glucose metabolism. DESIGN: We used cell...
Autores principales: | Gonzalez-Rellan, Maria J, Novoa, Eva, da Silva Lima, Natalia, Rodriguez, Amaia, Veyrat-Durebex, Christelle, Seoane, Samuel, Porteiro, Begoña, Fondevila, Marcos F, Fernandez, Uxia, Varela-Rey, Marta, Senra, Ana, Iglesias, Cristina, Escudero, Adriana, Fidalgo, Miguel, Guallar, Diana, Perez-Fernandez, Roman, Prevot, Vincent, Schwaninger, Markus, López, Miguel, Dieguez, Carlos, Coppari, Roberto, Frühbeck, Gema, Nogueiras, Ruben |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933162/ https://www.ncbi.nlm.nih.gov/pubmed/35580962 http://dx.doi.org/10.1136/gutjnl-2021-326620 |
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