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Hepatic p63 regulates glucose metabolism by repressing SIRT1

OBJECTIVE: p63 is a transcription factor within the p53 protein family that has key roles in development, differentiation and prevention of senescence, but its metabolic actions remain largely unknown. Herein, we investigated the physiological role of p63 in glucose metabolism. DESIGN: We used cell...

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Detalles Bibliográficos
Autores principales: Gonzalez-Rellan, Maria J, Novoa, Eva, da Silva Lima, Natalia, Rodriguez, Amaia, Veyrat-Durebex, Christelle, Seoane, Samuel, Porteiro, Begoña, Fondevila, Marcos F, Fernandez, Uxia, Varela-Rey, Marta, Senra, Ana, Iglesias, Cristina, Escudero, Adriana, Fidalgo, Miguel, Guallar, Diana, Perez-Fernandez, Roman, Prevot, Vincent, Schwaninger, Markus, López, Miguel, Dieguez, Carlos, Coppari, Roberto, Frühbeck, Gema, Nogueiras, Ruben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933162/
https://www.ncbi.nlm.nih.gov/pubmed/35580962
http://dx.doi.org/10.1136/gutjnl-2021-326620

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