Attenuation of Lipopolysaccharide-Induced Inflammatory Responses through Inhibition of the NF-κB Pathway and the Increased NRF2 Level by a Flavonol-Enriched n-Butanol Fraction from Uvaria alba

[Image: see text] Pathologic hyperreactive inflammatory responses occur when there is excessive activation of a proinflammatory NF-κB pathway and a reduced cytoprotective NRF2 cascade. The noncytotoxic, highly selective COX-2 inhibitory flavonol-enriched butanol fraction (UaB) from Uvaria alba (U. a...

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Detalles Bibliográficos
Autores principales: Notarte, Kin Israel R., Quimque, Mark Tristan J., Macaranas, Imee T., Khan, Abbas, Pastrana, Adriel M., Villaflores, Oliver B., Arturo, Hans Christian P., Pilapil IV, Delfin Yñigo H., Tan, Sophia Morgan M., Wei, Dong-Qing, Wenzel-Storjohann, Arlette, Tasdemir, Deniz, Yen, Chia-Hung, Ji, Seon Yeong, Kim, Gi-Young, Choi, Yung Hyun, Macabeo, Allan Patrick G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933231/
https://www.ncbi.nlm.nih.gov/pubmed/36816691
http://dx.doi.org/10.1021/acsomega.2c06451

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