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The economic impact of anastomotic leak after colorectal cancer surgery

OBJECTIVE: To determine the economic impact of the incremental consumption of resources for the diagnosis and treatment of anastomotic leak (AL) in patients after resection with anastomosis for colorectal cancer compared to patients without AL on the Spanish health system. METHOD: This study include...

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Autores principales: Flor-Lorente, Blas, Noguera-Aguilar, José Francisco, Delgado-Rivilla, Salvadora, García-González, José María, Rodriguez-Martín, Marcos, Salinas-Ortega, Laura, Casado, Miguel Ángel, Álvarez, María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933261/
https://www.ncbi.nlm.nih.gov/pubmed/36795234
http://dx.doi.org/10.1186/s13561-023-00425-y
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author Flor-Lorente, Blas
Noguera-Aguilar, José Francisco
Delgado-Rivilla, Salvadora
García-González, José María
Rodriguez-Martín, Marcos
Salinas-Ortega, Laura
Casado, Miguel Ángel
Álvarez, María
author_facet Flor-Lorente, Blas
Noguera-Aguilar, José Francisco
Delgado-Rivilla, Salvadora
García-González, José María
Rodriguez-Martín, Marcos
Salinas-Ortega, Laura
Casado, Miguel Ángel
Álvarez, María
author_sort Flor-Lorente, Blas
collection PubMed
description OBJECTIVE: To determine the economic impact of the incremental consumption of resources for the diagnosis and treatment of anastomotic leak (AL) in patients after resection with anastomosis for colorectal cancer compared to patients without AL on the Spanish health system. METHOD: This study included a literature review with parameters validated by experts and the development of a cost analysis model to estimate the incremental resource consumption of patients with AL versus those without. The patients were divided into three groups: 1) colon cancer (CC) with resection, anastomosis and AL; 2) rectal cancer (RC) with resection, anastomosis without protective stoma and AL; and 3) RC with resection, anastomosis with protective stoma and AL. RESULTS: The average total incremental cost per patient was €38,819 and €32,599 for CC and RC, respectively. The cost of AL diagnosis per patient was €1018 (CC) and €1030 (RC). The cost of AL treatment per patient in Group 1 ranged from €13,753 (type B) to €44,985 (type C + stoma), that in Group 2 ranged from €7348 (type A) to €44,398 (type C + stoma), and that in Group 3 ranged from €6197 (type A) to €34,414 (type C). Hospital stays represented the highest cost for all groups. In RC, protective stoma was found to minimize the economic consequences of AL. CONCLUSIONS: The appearance of AL generates a considerable increase in the consumption of health resources, mainly due to an increase in hospital stays. The more complex the AL, the higher the cost associated with its treatment. INTEREST OF THE STUDY: it is the first cost-analysis study of AL after CR surgery based on prospective, observational and multicenter studies, with a clear, accepted and uniform definition of AL and estimated over a period of 30 days. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13561-023-00425-y.
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spelling pubmed-99332612023-02-17 The economic impact of anastomotic leak after colorectal cancer surgery Flor-Lorente, Blas Noguera-Aguilar, José Francisco Delgado-Rivilla, Salvadora García-González, José María Rodriguez-Martín, Marcos Salinas-Ortega, Laura Casado, Miguel Ángel Álvarez, María Health Econ Rev Research OBJECTIVE: To determine the economic impact of the incremental consumption of resources for the diagnosis and treatment of anastomotic leak (AL) in patients after resection with anastomosis for colorectal cancer compared to patients without AL on the Spanish health system. METHOD: This study included a literature review with parameters validated by experts and the development of a cost analysis model to estimate the incremental resource consumption of patients with AL versus those without. The patients were divided into three groups: 1) colon cancer (CC) with resection, anastomosis and AL; 2) rectal cancer (RC) with resection, anastomosis without protective stoma and AL; and 3) RC with resection, anastomosis with protective stoma and AL. RESULTS: The average total incremental cost per patient was €38,819 and €32,599 for CC and RC, respectively. The cost of AL diagnosis per patient was €1018 (CC) and €1030 (RC). The cost of AL treatment per patient in Group 1 ranged from €13,753 (type B) to €44,985 (type C + stoma), that in Group 2 ranged from €7348 (type A) to €44,398 (type C + stoma), and that in Group 3 ranged from €6197 (type A) to €34,414 (type C). Hospital stays represented the highest cost for all groups. In RC, protective stoma was found to minimize the economic consequences of AL. CONCLUSIONS: The appearance of AL generates a considerable increase in the consumption of health resources, mainly due to an increase in hospital stays. The more complex the AL, the higher the cost associated with its treatment. INTEREST OF THE STUDY: it is the first cost-analysis study of AL after CR surgery based on prospective, observational and multicenter studies, with a clear, accepted and uniform definition of AL and estimated over a period of 30 days. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13561-023-00425-y. Springer Berlin Heidelberg 2023-02-16 /pmc/articles/PMC9933261/ /pubmed/36795234 http://dx.doi.org/10.1186/s13561-023-00425-y Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Flor-Lorente, Blas
Noguera-Aguilar, José Francisco
Delgado-Rivilla, Salvadora
García-González, José María
Rodriguez-Martín, Marcos
Salinas-Ortega, Laura
Casado, Miguel Ángel
Álvarez, María
The economic impact of anastomotic leak after colorectal cancer surgery
title The economic impact of anastomotic leak after colorectal cancer surgery
title_full The economic impact of anastomotic leak after colorectal cancer surgery
title_fullStr The economic impact of anastomotic leak after colorectal cancer surgery
title_full_unstemmed The economic impact of anastomotic leak after colorectal cancer surgery
title_short The economic impact of anastomotic leak after colorectal cancer surgery
title_sort economic impact of anastomotic leak after colorectal cancer surgery
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933261/
https://www.ncbi.nlm.nih.gov/pubmed/36795234
http://dx.doi.org/10.1186/s13561-023-00425-y
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