Contraction of human brain vascular pericytes in response to islet amyloid polypeptide is reversed by pramlintide

The islet amyloid polypeptide (IAPP), a pancreas-produced peptide, has beneficial functions in its monomeric form. However, IAPP aggregates, related to type 2 diabetes mellitus (T2DM), are toxic not only for the pancreas, but also for the brain. In the latter, IAPP is often found in vessels, where i...

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Detalles Bibliográficos
Autores principales: Nuñez-Diaz, Cristina, Pocevičiūtė, Dovilė, Schultz, Nina, Welinder, Charlotte, Swärd, Karl, Wennström, Malin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933335/
https://www.ncbi.nlm.nih.gov/pubmed/36793056
http://dx.doi.org/10.1186/s13041-023-01013-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933335/
https://www.ncbi.nlm.nih.gov/pubmed/36793056
http://dx.doi.org/10.1186/s13041-023-01013-1

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