Cargando…

PKCδ promotes the invasion and migration of colorectal cancer through c-myc/NDRG1 pathway

OBJECTIVE: Colorectal cancer (CRC) is the third cause of expected cancer deaths both in men and women in the U.S. and the third most commonly diagnosed cancer in China Targeted therapy has been proven to improve overall survival for unresectable metastatic CRC. But the location of the primary tumor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jia, Hong-tao, Shao, Yan-fei, Zhou, Xue-liang, Yang, Guang, Huang, Ling, Aikemu, Batuer, Li, Shu-chun, Ding, Cheng-sheng, Fan, Xiao-dong, Hong, Hi-ju, Zhang, Sen, Pan, Rui-jun, Sun, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933346/ https://www.ncbi.nlm.nih.gov/pubmed/36816970 http://dx.doi.org/10.3389/fonc.2023.1026561

Ejemplares similares

NDRG1 regulates Filopodia-induced Colorectal Cancer invasiveness via modulating CDC42 activity
por: Aikemu, Batuer, et al.
Publicado: (2021)

NDRG1 enhances the sensitivity of cetuximab by modulating EGFR trafficking in colorectal cancer
por: Yang, Guang, et al.
Publicado: (2021)

An Original Ferroptosis-Related Gene Signature Effectively Predicts the Prognosis and Clinical Status for Colorectal Cancer Patients
por: Shao, Yanfei, et al.
Publicado: (2021)

Kaempferol exhibits a synergistic effect with doxorubicin to inhibit proliferation, migration, and invasion of liver cancer
por: Yang, Guang, et al.
Publicado: (2021)

ACACB is a novel metabolism-related biomarker in the prediction of response to cetuximab therapy inmetastatic colorectal cancer: ACACB is a biomarker for CTX therapy in metastatic CRC
por: Hong, Hi-Ju, et al.
Publicado: (2022)

Clinical Diagnostic and Prognostic Potential of NDRG1 and NDRG2 in Hepatocellular Carcinoma Patients
por: Xu, Shaohua, et al.
Publicado: (2022)

Artificial Intelligence in Decision-Making for Colorectal Cancer Treatment Strategy: An Observational Study of Implementing Watson for Oncology in a 250-Case Cohort
por: Aikemu, Batuer, et al.
Publicado: (2021)

Genomic signature of MTOR could be an immunogenicity marker in human colorectal cancer
por: Wang, Chenxing, et al.
Publicado: (2022)

N-myc downstream-regulated gene 1 inhibits the proliferation of colorectal cancer through emulative antagonizing NEDD4-mediated ubiquitylation of p21
por: Zhang, Sen, et al.
Publicado: (2019)

PKCα and PKCδ: Friends and Rivals
por: Black, Jennifer D., et al.
Publicado: (2022)

Suppression of EGFR/PKC-δ/NF-κB Signaling Associated With Imipramine-Inhibited Progression of Non-Small Cell Lung Cancer
por: Yueh, Po-Fu, et al.
Publicado: (2021)

B7-H4 expression is upregulated by PKCδ activation and contributes to PKCδ-induced cell motility in colorectal cancer
por: Zhou, Bin, et al.
Publicado: (2022)

Stabilization of Sur8 via PKCα/δ degradation promotes transformation and migration of colorectal cancer cells
por: Lee, Kug Hwa, et al.
Publicado: (2017)

Tumor suppressor NDRG2 inhibits glycolysis and glutaminolysis in colorectal cancer cells by repressing c-Myc expression
por: Xu, Xinyuan, et al.
Publicado: (2015)

Comprehensive exploration of tumor immune microenvironment feature and therapeutic response in colorectal cancer based on a novel immune-related long non-coding RNA prognostic signature
por: Zhou, Xueliang, et al.
Publicado: (2022)

Comprehensive Analysis of Ferroptosis-Related Markers for the Clinical and Biological Value in Gastric Cancer
por: Shao, Yanfei, et al.
Publicado: (2021)

The Metastasis Suppressor, N-myc Downregulated Gene 1 (NDRG1), Is a Prognostic Biomarker for Human Colorectal Cancer
por: Mao, Zhihai, et al.
Publicado: (2013)

Differential Roles of the PKC Novel Isoforms, PKCδ and PKCε, in Mouse and Human Platelets
por: Pears, Catherine J., et al.
Publicado: (2008)

PKCδ Blues for the β-Cell
por: Schmitz-Peiffer, Carsten, et al.
Publicado: (2010)

Exploring the relationship between lactate metabolism and immunological function in colorectal cancer through genes identification and analysis
por: Zhang, Enkui, et al.
Publicado: (2023)

Src, PKCα, and PKCδ are required for αvβ3 integrin-mediated metastatic melanoma invasion
por: Putnam, Andrew J, et al.
Publicado: (2009)

Overexpressed PKCδ Downregulates the Expression of PKCα in B16F10 Melanoma: Induction of Apoptosis by PKCδ via Ceramide Generation
por: Halder, Kuntal, et al.
Publicado: (2014)

Emerging role of N-myc downstream-regulated gene 2 (NDRG2) in cancer
por: Hu, Wei, et al.
Publicado: (2015)

NDRG2 inhibits hepatocellular carcinoma adhesion, migration and invasion by regulating CD24 expression
por: Zheng, Jin, et al.
Publicado: (2011)

Molecular Mechanisms by Which S100A4 Regulates the Migration and Invasion of PGCCs With Their Daughter Cells in Human Colorectal Cancer
por: Fei, Fei, et al.
Publicado: (2020)

PKCα Modulates Epithelial-to-Mesenchymal Transition and Invasiveness of Breast Cancer Cells Through ZEB1
por: Llorens, María Candelaria, et al.
Publicado: (2019)

The metastatic suppressor NDRG1 inhibits EMT, migration and invasion through interaction and promotion of caveolin-1 ubiquitylation in human colorectal cancer cells
por: Mi, L, et al.
Publicado: (2017)

N-myc Downstream-Regulated Gene 2 (NDRG2) Function as a Positive Regulator of Apoptosis: A New Insight into NDRG2 as a Tumor Suppressor
por: Kim, Gayeon, et al.
Publicado: (2021)

Overexpression of N-Myc Downstream-Regulated Gene 2 (NDRG2) Regulates the Proliferation and Invasion of Bladder Cancer Cells In Vitro and In Vivo
por: Li, Ruixiao, et al.
Publicado: (2013)

Polyamine metabolism patterns characterized tumor microenvironment, prognosis, and response to immunotherapy in colorectal cancer
por: Zhang, Enkui, et al.
Publicado: (2023)

NDRG2 Controls COX-2/PGE(2)-Mediated Breast Cancer Cell Migration and Invasion
por: Kim, Myung-Jin, et al.
Publicado: (2014)

MYC Immunohistochemistry Predicts MYC Rearrangements by FISH
por: Nwanze, Julum, et al.
Publicado: (2017)

Structured training curricula for robotic colorectal surgery in China: does laparoscopic experience affect training effects?
por: Shu, Duohuo, et al.
Publicado: (2023)

Quercetin Directly Targets JAK2 and PKCδ and Prevents UV-Induced Photoaging in Human Skin
por: Shin, Eun Ju, et al.
Publicado: (2019)

PKCδ regulates the vascular biology in diabetic atherosclerosis
por: Qin, Peiliang, et al.
Publicado: (2023)

PKCδ deficiency inhibits fetal development and is associated with heart elastic fiber hyperplasia and lung inflammation in adult PKCδ knockout mice
por: Niino, Yuko S., et al.
Publicado: (2021)

PMA inhibits endothelial cell migration through activating the PKC-δ/Syk/NF-κB-mediated up-regulation of Thy-1
por: Wen, Heng-Ching, et al.
Publicado: (2018)

Role and Mechanism of PKC-δ for Cardiovascular Disease: Current Status and Perspective
por: Miao, Li-na, et al.
Publicado: (2022)

A Deletion in the N-Myc Downstream Regulated Gene 1 (NDRG1) Gene in Greyhounds with Polyneuropathy
por: Drögemüller, Cord, et al.
Publicado: (2010)

Expression of merlin, NDRG2, ERBB2, and c-MYC in meningiomas: relationship with tumor grade and recurrence
por: Ongaratti, B.R., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_8fv3cpuhqo1c2km5r1hc3503ej