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The tamoxifen-regulated, long non-coding RNA LINC00992 affects proliferation, migration, and expression of tamoxifen resistance-associated genes in MCF-7 breast cancer cells

INTRODUCTION: Tamoxifen-adapted MCF-7 breast cancer cells (MCF-7-TAM-R) are a model for acquired tamoxifen resistance in oestrogen receptor-positive breast cancer. In this system, the expression of long-non-coding RNA LINC00992 is decreased. LINC00992 might therefore contribute to tamoxifen adaption...

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Detalles Bibliográficos
Autores principales: Graf, Sebastian, Haybaeck, Johannes, Behre, Gerhard, Kalinski, Thomas, Nass, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933353/
https://www.ncbi.nlm.nih.gov/pubmed/36816389
http://dx.doi.org/10.5114/wo.2023.125000