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Hypofractionated radiotherapy for renal cell carcinoma with inferior vena cava tumour thrombus

Renal cell carcinoma (RCC) constitutes about 3% of all malignant neoplasms in adults. Clear cell carcinoma is the most frequent type, accounting for about 65% of cases. It tends to invade the veins and form tumour thrombi in inferior vena cava (IVC-TT), occasionally reaching the right atrium. Nephre...

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Autores principales: Bełdzińska, Karolina, Gądek, Konrad, Rutkowski, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933356/
https://www.ncbi.nlm.nih.gov/pubmed/36816397
http://dx.doi.org/10.5114/wo.2023.124792
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author Bełdzińska, Karolina
Gądek, Konrad
Rutkowski, Jacek
author_facet Bełdzińska, Karolina
Gądek, Konrad
Rutkowski, Jacek
author_sort Bełdzińska, Karolina
collection PubMed
description Renal cell carcinoma (RCC) constitutes about 3% of all malignant neoplasms in adults. Clear cell carcinoma is the most frequent type, accounting for about 65% of cases. It tends to invade the veins and form tumour thrombi in inferior vena cava (IVC-TT), occasionally reaching the right atrium. Nephrectomy and thrombectomy are standard therapeutic procedures performed in RCC-IVC-TT. Despite proven effectiveness of surgery, this entity in IVC-TT is associated with poor outcome. The role of palliative radiotherapy in this entity is undetermined. We present a case of a 43-year-old female patient after right-sided nephrectomy due to advanced RCC which invaded the IVC, hepatic veins, and right atrium. The patient has been treated with postoperative, hypofractionated radiotherapy on the residual disease.
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spelling pubmed-99333562023-02-17 Hypofractionated radiotherapy for renal cell carcinoma with inferior vena cava tumour thrombus Bełdzińska, Karolina Gądek, Konrad Rutkowski, Jacek Contemp Oncol (Pozn) Case Report Renal cell carcinoma (RCC) constitutes about 3% of all malignant neoplasms in adults. Clear cell carcinoma is the most frequent type, accounting for about 65% of cases. It tends to invade the veins and form tumour thrombi in inferior vena cava (IVC-TT), occasionally reaching the right atrium. Nephrectomy and thrombectomy are standard therapeutic procedures performed in RCC-IVC-TT. Despite proven effectiveness of surgery, this entity in IVC-TT is associated with poor outcome. The role of palliative radiotherapy in this entity is undetermined. We present a case of a 43-year-old female patient after right-sided nephrectomy due to advanced RCC which invaded the IVC, hepatic veins, and right atrium. The patient has been treated with postoperative, hypofractionated radiotherapy on the residual disease. Termedia Publishing House 2022-12-30 2022 /pmc/articles/PMC9933356/ /pubmed/36816397 http://dx.doi.org/10.5114/wo.2023.124792 Text en Copyright © 2022 Termedia https://creativecommons.org/licenses/by-nc-sa/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0). License (http://creativecommons.org/licenses/by-nc-sa/4.0/ (https://creativecommons.org/licenses/by-nc-sa/4.0/) )
spellingShingle Case Report
Bełdzińska, Karolina
Gądek, Konrad
Rutkowski, Jacek
Hypofractionated radiotherapy for renal cell carcinoma with inferior vena cava tumour thrombus
title Hypofractionated radiotherapy for renal cell carcinoma with inferior vena cava tumour thrombus
title_full Hypofractionated radiotherapy for renal cell carcinoma with inferior vena cava tumour thrombus
title_fullStr Hypofractionated radiotherapy for renal cell carcinoma with inferior vena cava tumour thrombus
title_full_unstemmed Hypofractionated radiotherapy for renal cell carcinoma with inferior vena cava tumour thrombus
title_short Hypofractionated radiotherapy for renal cell carcinoma with inferior vena cava tumour thrombus
title_sort hypofractionated radiotherapy for renal cell carcinoma with inferior vena cava tumour thrombus
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933356/
https://www.ncbi.nlm.nih.gov/pubmed/36816397
http://dx.doi.org/10.5114/wo.2023.124792
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