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AAV-glycine receptor α3 alleviates CFA-induced inflammatory pain by downregulating ERK phosphorylation and proinflammatory cytokine expression in SD rats

BACKGROUND: Glycine receptors (GlyRs) play key roles in the processing of inflammatory pain. The use of adeno-associated virus (AAV) vectors for gene therapy in human clinical trials has shown promise, as AAV generally causes a very mild immune response and long-term gene transfer, and there have be...

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Detalles Bibliográficos
Autores principales:	Wang, Hung-Chen, Cheng, Kuang-I, Tseng, Kuang-Yi, Kwan, Aij-Lie, Chang, Lin-Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933394/ https://www.ncbi.nlm.nih.gov/pubmed/36792984 http://dx.doi.org/10.1186/s10020-023-00606-9

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