Introducing carbohydrate patterning in mannose-decorated supramolecular assemblies and hydrogels

Benzene-1,3,5-tricarboxamide (BTA) glyco-monomers containing one, two or three mannose units are synthesized and formulated into differently patterned supramolecular glycopolymers through homo-assembly or co-assembly with non-functionalized BTAs. Unfortunately, no cellular activity could be detected...

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Detalles Bibliográficos
Autores principales: Rijns, Laura, Su, Lu, Maxeiner, Konrad, Morgese, Giulia, Ng, David Y. W., Weil, Tanja, Dankers, Patricia Y. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933453/
https://www.ncbi.nlm.nih.gov/pubmed/36723198
http://dx.doi.org/10.1039/d2cc06064g
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author Rijns, Laura
Su, Lu
Maxeiner, Konrad
Morgese, Giulia
Ng, David Y. W.
Weil, Tanja
Dankers, Patricia Y. W.
author_facet Rijns, Laura
Su, Lu
Maxeiner, Konrad
Morgese, Giulia
Ng, David Y. W.
Weil, Tanja
Dankers, Patricia Y. W.
author_sort Rijns, Laura
collection PubMed
description Benzene-1,3,5-tricarboxamide (BTA) glyco-monomers containing one, two or three mannose units are synthesized and formulated into differently patterned supramolecular glycopolymers through homo-assembly or co-assembly with non-functionalized BTAs. Unfortunately, no cellular activity could be detected. Excitingly, these glyco-BTA monomers could be formulated into hydrogels, paving the way for (immune) cell culture.
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spelling pubmed-99334532023-02-17 Introducing carbohydrate patterning in mannose-decorated supramolecular assemblies and hydrogels Rijns, Laura Su, Lu Maxeiner, Konrad Morgese, Giulia Ng, David Y. W. Weil, Tanja Dankers, Patricia Y. W. Chem Commun (Camb) Chemistry Benzene-1,3,5-tricarboxamide (BTA) glyco-monomers containing one, two or three mannose units are synthesized and formulated into differently patterned supramolecular glycopolymers through homo-assembly or co-assembly with non-functionalized BTAs. Unfortunately, no cellular activity could be detected. Excitingly, these glyco-BTA monomers could be formulated into hydrogels, paving the way for (immune) cell culture. The Royal Society of Chemistry 2023-01-31 /pmc/articles/PMC9933453/ /pubmed/36723198 http://dx.doi.org/10.1039/d2cc06064g Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Rijns, Laura
Su, Lu
Maxeiner, Konrad
Morgese, Giulia
Ng, David Y. W.
Weil, Tanja
Dankers, Patricia Y. W.
Introducing carbohydrate patterning in mannose-decorated supramolecular assemblies and hydrogels
title Introducing carbohydrate patterning in mannose-decorated supramolecular assemblies and hydrogels
title_full Introducing carbohydrate patterning in mannose-decorated supramolecular assemblies and hydrogels
title_fullStr Introducing carbohydrate patterning in mannose-decorated supramolecular assemblies and hydrogels
title_full_unstemmed Introducing carbohydrate patterning in mannose-decorated supramolecular assemblies and hydrogels
title_short Introducing carbohydrate patterning in mannose-decorated supramolecular assemblies and hydrogels
title_sort introducing carbohydrate patterning in mannose-decorated supramolecular assemblies and hydrogels
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933453/
https://www.ncbi.nlm.nih.gov/pubmed/36723198
http://dx.doi.org/10.1039/d2cc06064g
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