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Site-Selective Synthesis of C-17 Ester Derivatives of Natural Andrographolide for Evaluation as a Potential Anticancer Agent

[Image: see text] A library of 57 compounds of natural andrographolide was designed, synthesized, and screened for in vitro studies against four human cancer cell lines: A594, PC-3, MCF-7, and HCT-116. Most of the synthesized compounds displayed better cytotoxic profile against all tested cells comp...

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Detalles Bibliográficos
Autores principales: Kumar, Gulshan, Thapa, Sonia, Tali, Javeed Ahmad, Singh, Davinder, Sharma, Bhupesh Kumar, Panda, Kamakshya Nath, Singh, Shashank K., Shankar, Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933479/
https://www.ncbi.nlm.nih.gov/pubmed/36816646
http://dx.doi.org/10.1021/acsomega.3c00036