CD103 and CD39 coexpression identifies neoantigen-specific cytotoxic T cells in colorectal cancers with low mutation burden

BACKGROUND: Expression of CD103 and CD39 has been found to pinpoint tumor-reactive CD8(+) T cells in a variety of solid cancers. We aimed to investigate whether these markers specifically identify neoantigen-specific T cells in colorectal cancers (CRCs) with low mutation burden. EXPERIMENTAL DESIGN:...

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Detalles Bibliográficos
Autores principales: van den Bulk, Jitske, van der Ploeg, Manon, Ijsselsteijn, Marieke E, Ruano, Dina, van der Breggen, Ruud, Duhen, Rebekka, Peeters, Koen C M J, Fariña-Sarasqueta, Arantza, Verdegaal, Els M E, van der Burg, Sjoerd H, Duhen, Thomas, de Miranda, Noel F C C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933759/
https://www.ncbi.nlm.nih.gov/pubmed/36792124
http://dx.doi.org/10.1136/jitc-2022-005887

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933759/
https://www.ncbi.nlm.nih.gov/pubmed/36792124
http://dx.doi.org/10.1136/jitc-2022-005887

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