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Senescent cancer cell vaccines induce cytotoxic T cell responses targeting primary tumors and disseminated tumor cells

BACKGROUND: Immune tolerance contributes to resistance to conventional cancer therapies such as radiation. Radiotherapy induces immunogenic cell death, releasing a burst of tumor antigens, but this appears insufficient to stimulate an effective antitumor immune response. Radiation also increases inf...

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Detalles Bibliográficos
Autores principales:	Liu, Yue, Pagacz, Joanna, Wolfgeher, Donald J, Bromerg, Kenneth D, Gorman, Jacob V, Kron, Stephen J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2023
Materias:	Clinical/Translational Cancer Immunotherapy
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933761/ https://www.ncbi.nlm.nih.gov/pubmed/36792123 http://dx.doi.org/10.1136/jitc-2022-005862

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