High SARS-CoV-2 tropism and activation of immune cells in the testes of non-vaccinated deceased COVID-19 patients

BACKGROUND: Cellular entry of SARS-CoV-2 has been shown to rely on angiotensin-converting enzyme 2 (ACE2) receptors, whose expression in the testis is among the highest in the body. Additionally, the risk of mortality seems higher among male COVID-19 patients, and though much has been published sinc...

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Detalles Bibliográficos
Autores principales: Costa, Guilherme M. J., Lacerda, Samyra M. S. N., Figueiredo, André F. A., Wnuk, Natália T., Brener, Marcos R. G., Andrade, Lídia M., Campolina-Silva, Gabriel H., Kauffmann-Zeh, Andrea, Pacifico, Lucila G. G., Versiani, Alice F., Antunes, Maísa M., Souza, Fernanda R., Cassali, Geovanni D., Caldeira-Brant, André L., Chiarini-Garcia, Hélio, de Souza, Fernanda G., Costa, Vivian V., da Fonseca, Flavio G., Nogueira, Maurício L., Campos, Guilherme R. F., Kangussu, Lucas M., Martins, Estefânia M. N., Antonio, Loudiana M., Bittar, Cintia, Rahal, Paula, Aguiar, Renato S., Mendes, Bárbara P., Procópio, Marcela S., Furtado, Thiago P., Guimaraes, Yuri L., Menezes, Gustavo B., Martinez-Marchal, Ana, Orwig, Kyle E., Brieño-Enríquez, Miguel, Furtado, Marcelo H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933832/
https://www.ncbi.nlm.nih.gov/pubmed/36797789
http://dx.doi.org/10.1186/s12915-022-01497-8

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