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LINCs Are Vulnerable to Epileptic Insult and Fail to Provide Seizure Control via On-Demand Activation

Temporal lobe epilepsy (TLE) is notoriously pharmacoresistant, and identifying novel therapeutic targets for controlling seizures is crucial. Long-range inhibitory neuronal nitric oxide synthase-expressing cells (LINCs), a population of hippocampal neurons, were recently identified as a unique sourc...

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Detalles Bibliográficos
Autores principales: Stieve, Bethany J., Smith, Madison M., Krook-Magnuson, Esther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933934/
https://www.ncbi.nlm.nih.gov/pubmed/36725340
http://dx.doi.org/10.1523/ENEURO.0195-22.2022