Cargando…
LINCs Are Vulnerable to Epileptic Insult and Fail to Provide Seizure Control via On-Demand Activation
Temporal lobe epilepsy (TLE) is notoriously pharmacoresistant, and identifying novel therapeutic targets for controlling seizures is crucial. Long-range inhibitory neuronal nitric oxide synthase-expressing cells (LINCs), a population of hippocampal neurons, were recently identified as a unique sourc...
Autores principales: | Stieve, Bethany J., Smith, Madison M., Krook-Magnuson, Esther |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933934/ https://www.ncbi.nlm.nih.gov/pubmed/36725340 http://dx.doi.org/10.1523/ENEURO.0195-22.2022 |
Ejemplares similares
-
On-demand optogenetic control of spontaneous seizures in temporal lobe epilepsy
por: Krook-Magnuson, Esther, et al.
Publicado: (2013) -
Cerebellar Directed Optogenetic Intervention Inhibits Spontaneous Hippocampal Seizures in a Mouse Model of Temporal Lobe Epilepsy1
2
por: Krook-Magnuson, Esther, et al.
Publicado: (2014) -
Targeting the Mouse Ventral Hippocampus in the Intrahippocampal Kainic Acid Model of Temporal Lobe Epilepsy
por: Zeidler, Zachary, et al.
Publicado: (2018) -
The Devil’s in the Details: How to Harness Inhibition for Seizure Control
por: Krook-Magnuson, Esther
Publicado: (2020) -
Adaptation and Inhibition Control Pathological Synchronization in a Model of Focal Epileptic Seizure
por: Buchin, Anatoly, et al.
Publicado: (2018)