In vivo characterization of cerebrovascular impairment induced by amyloid β peptide overload in glymphatic clearance system using swept-source optical coherence tomography

SIGNIFICANCE: Antiamyloid [Formula: see text] ([Formula: see text]) immunotherapy is a promising therapeutic strategy for Alzheimer’s disease (AD) but generates large amounts of soluble [Formula: see text] peptides that could overwhelm the clearance pathway, leading to serious side effects. Direct i...

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Detalles Bibliográficos
Autores principales: Yu, Yao, Zhang, Ning, Xiang, Ben, Ding, Ning, Liu, Jian, Huang, Jiangmei, Zhao, Min, Zhao, Yuqian, Wang, Yi, Ma, Zhenhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Photo-Optical Instrumentation Engineers 2023
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933996/
https://www.ncbi.nlm.nih.gov/pubmed/36817752
http://dx.doi.org/10.1117/1.NPh.10.1.015005

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