KCNH2 encodes a nuclear-targeted polypeptide that mediates hERG1 channel gating and expression

KCNH2 encodes hERG1, the voltage-gated potassium channel that conducts the rapid delayed rectifier potassium current (I(Kr)) in human cardiac tissue. hERG1 is one of the first channels expressed during early cardiac development, and its dysfunction is associated with intrauterine fetal death, sudden...

Descripción completa

Detalles Bibliográficos
Autores principales: Jain, Abhilasha, Stack, Olivia, Ghodrati, Saba, Sanchez-Conde, Francisco G., Ukachukwu, Chiamaka U., Salwi, Shreya, Jimenez-Vazquez, Eric N., Jones, David K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934303/
https://www.ncbi.nlm.nih.gov/pubmed/36626562
http://dx.doi.org/10.1073/pnas.2214700120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934303/
https://www.ncbi.nlm.nih.gov/pubmed/36626562
http://dx.doi.org/10.1073/pnas.2214700120

Ejemplares similares