Cell-specific imputation of drug connectivity mapping with incomplete data

Drug repositioning allows expedited discovery of new applications for existing compounds, but re-screening vast compound libraries is often prohibitively expensive. “Connectivity mapping” is a process that links drugs to diseases by identifying compounds whose impact on expression in a collection of...

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Detalles Bibliográficos
Autores principales: Sapashnik, Diana, Newman, Rebecca, Pietras, Christopher Michael, Zhou, Di, Devkota, Kapil, Qu, Fangfang, Kofman, Lior, Boudreau, Sean, Fried, Inbar, Slonim, Donna K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934325/
https://www.ncbi.nlm.nih.gov/pubmed/36795645
http://dx.doi.org/10.1371/journal.pone.0278289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934325/
https://www.ncbi.nlm.nih.gov/pubmed/36795645
http://dx.doi.org/10.1371/journal.pone.0278289

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