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Cumulative damage for multi-type epidemics and an application to infectious diseases
A continuous time multivariate stochastic model is proposed for assessing the damage of a multi-type epidemic cause to a population as it unfolds. The instants when cases occur and the magnitude of their injure are random. Thus, we define a cumulative damage based on counting processes and a multiva...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Berlin Heidelberg
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934514/ https://www.ncbi.nlm.nih.gov/pubmed/36797526 http://dx.doi.org/10.1007/s00285-023-01880-1 |
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author | Fierro, Raúl |
author_facet | Fierro, Raúl |
author_sort | Fierro, Raúl |
collection | PubMed |
description | A continuous time multivariate stochastic model is proposed for assessing the damage of a multi-type epidemic cause to a population as it unfolds. The instants when cases occur and the magnitude of their injure are random. Thus, we define a cumulative damage based on counting processes and a multivariate mark process. For a large population we approximate the behavior of this damage process by its asymptotic distribution. Also, we analyze the distribution of the stopping times when the numbers of cases caused by the epidemic attain levels beyond certain thresholds. We focus on introducing some tools for statistical inference on the parameters related with the epidemic. In this regard, we present a general hypothesis test for homogeneity in epidemics and apply it to data of Covid-19 in Chile. |
format | Online Article Text |
id | pubmed-9934514 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-99345142023-02-17 Cumulative damage for multi-type epidemics and an application to infectious diseases Fierro, Raúl J Math Biol Article A continuous time multivariate stochastic model is proposed for assessing the damage of a multi-type epidemic cause to a population as it unfolds. The instants when cases occur and the magnitude of their injure are random. Thus, we define a cumulative damage based on counting processes and a multivariate mark process. For a large population we approximate the behavior of this damage process by its asymptotic distribution. Also, we analyze the distribution of the stopping times when the numbers of cases caused by the epidemic attain levels beyond certain thresholds. We focus on introducing some tools for statistical inference on the parameters related with the epidemic. In this regard, we present a general hypothesis test for homogeneity in epidemics and apply it to data of Covid-19 in Chile. Springer Berlin Heidelberg 2023-02-16 2023 /pmc/articles/PMC9934514/ /pubmed/36797526 http://dx.doi.org/10.1007/s00285-023-01880-1 Text en © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2023, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Article Fierro, Raúl Cumulative damage for multi-type epidemics and an application to infectious diseases |
title | Cumulative damage for multi-type epidemics and an application to infectious diseases |
title_full | Cumulative damage for multi-type epidemics and an application to infectious diseases |
title_fullStr | Cumulative damage for multi-type epidemics and an application to infectious diseases |
title_full_unstemmed | Cumulative damage for multi-type epidemics and an application to infectious diseases |
title_short | Cumulative damage for multi-type epidemics and an application to infectious diseases |
title_sort | cumulative damage for multi-type epidemics and an application to infectious diseases |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934514/ https://www.ncbi.nlm.nih.gov/pubmed/36797526 http://dx.doi.org/10.1007/s00285-023-01880-1 |
work_keys_str_mv | AT fierroraul cumulativedamageformultitypeepidemicsandanapplicationtoinfectiousdiseases |