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Clustering-independent estimation of cell abundances in bulk tissues using single-cell RNA-seq data
Single-cell RNA-sequencing has transformed the study of biological tissues by enabling transcriptomic characterizations of their constituent cell states. Computational methods for gene expression deconvolution use this information to infer the cell composition of related tissues profiled at the bulk...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934539/ https://www.ncbi.nlm.nih.gov/pubmed/36798206 http://dx.doi.org/10.1101/2023.02.06.527318 |