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Mitochondrial metabolism in primary and metastatic human kidney cancers

Most kidney cancers display evidence of metabolic dysfunction(1–4) but how this relates to cancer progression in humans is unknown. We used a multidisciplinary approach to infuse (13)C-labeled nutrients during surgical tumour resection in over 70 patients with kidney cancer. Labeling from [U-(13)C]g...

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Detalles Bibliográficos
Autores principales: Bezwada, Divya, Lesner, Nicholas P., Brooks, Bailey, Vu, Hieu S., Wu, Zheng, Cai, Ling, Kasitinon, Stacy, Kelekar, Sherwin, Cai, Feng, Aurora, Arin B., Patrick, McKenzie, Leach, Ashley, Ghandour, Rashed, Zhang, Yuanyuan, Do, Duyen, Sudderth, Jessica, Dumesnil, Dennis, House, Sara, Rosales, Tracy, Poole, Alan M., Lotan, Yair, Woldu, Solomon, Bagrodia, Aditya, Meng, Xiaosong, Cadeddu, Jeffrey A., Mishra, Prashant, Pedrosa, Ivan, Kapur, Payal, Courtney, Kevin D., Malloy, Craig R., Margulis, Vitaly, DeBerardinis, Ralph J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934542/
https://www.ncbi.nlm.nih.gov/pubmed/36798172
http://dx.doi.org/10.1101/2023.02.06.527285

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