The BAF chromatin complex component SMARCC1 does not mediate GLI transcriptional repression of Hedgehog target genes in limb buds

Transcriptional responses to the Hedgehog (HH) signaling pathway are primarily modulated by GLI repression in the mouse limb. Previous studies suggested a role for the BAF chromatin remodeling complex in mediating GLI repression. Consistent with this possibility, the core BAF complex protein SMARCC1...

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Detalles Bibliográficos
Autores principales: Ramachandran, Janani, Chen, Wanlu, Lex, Rachel K., Windsor, Kathryn E., Lee, Hyunji, Wang, Tingchang, Zhou, Weiqiang, Ji, Hongkai, Vokes, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934545/
https://www.ncbi.nlm.nih.gov/pubmed/36798239
http://dx.doi.org/10.1101/2023.02.03.527038

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