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Differential miRNA Expression Contributes to Emergence of Multiple Cancer Stem Cell Subpopulations in Human Colorectal Cancer

One reason for lack of efficacy in cancer therapeutics is tumor heterogeneity. We hypothesize that tumor heterogeneity arises due to emergence of multiple cancer stem cell (CSC) subpopulations because miRNAs regulate expression of stem cell genes in CSCs. Our goal was to determine if: i) multiple CS...

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Detalles Bibliográficos
Autores principales:	Stark, Victoria A., Facey, Caroline O. B., Opdenaker, Lynn, Fields, Jeremy Z., Boman, Bruce M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934564/ https://www.ncbi.nlm.nih.gov/pubmed/36798319 http://dx.doi.org/10.1101/2023.02.06.527341

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