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Target-specific requirements for RNA interference can be explained by a single regulatory network

Since double-stranded RNA (dsRNA) is effective for silencing a wide variety of genes, all genes are typically considered equivalent targets for such RNA interference (RNAi). Yet, loss of some regulators of RNAi in the nematode C. elegans can selectively impair the silencing of some genes, raising th...

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Detalles Bibliográficos
Autores principales: Knudsen, Daphne R., Raman, Pravrutha, Ettefa, Farida, De Ravin, Laura, Jose, Antony M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934570/
https://www.ncbi.nlm.nih.gov/pubmed/36798330
http://dx.doi.org/10.1101/2023.02.07.527351