Cargando…

Target-specific requirements for RNA interference can be explained by a single regulatory network

Since double-stranded RNA (dsRNA) is effective for silencing a wide variety of genes, all genes are typically considered equivalent targets for such RNA interference (RNAi). Yet, loss of some regulators of RNAi in the nematode C. elegans can selectively impair the silencing of some genes, raising th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Knudsen, Daphne R., Raman, Pravrutha, Ettefa, Farida, De Ravin, Laura, Jose, Antony M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934570/ https://www.ncbi.nlm.nih.gov/pubmed/36798330 http://dx.doi.org/10.1101/2023.02.07.527351

Ejemplares similares

Mating can initiate stable RNA silencing that overcomes epigenetic recovery
por: Devanapally, Sindhuja, et al.
Publicado: (2021)

The double-stranded RNA binding protein RDE-4 can act cell autonomously during feeding RNAi in C. elegans
por: Raman, Pravrutha, et al.
Publicado: (2017)

Single-cell gene regulatory network prediction by explainable AI
por: Keyl, Philipp, et al.
Publicado: (2023)

Network Topology Can Explain Differences in Pleiotropy Between Cis- and Trans-regulatory Mutations
por: Vande Zande, Pétra, et al.
Publicado: (2022)

Condensation of LINE-1 is critical for retrotransposition
por: Sil, Srinjoy, et al.
Publicado: (2023)

Can the Content of Social Networks Explain Epidemic Outbreaks?
por: Gori Maia, Alexandre, et al.
Publicado: (2023)

Recurrent but Short-Lived Duplications of Centromeric Proteins in Holocentric Caenorhabditis Species
por: Caro, Lews, et al.
Publicado: (2022)

Recurrent interactions can explain the variance in single trial responses
por: Kotekal, Subhodh, et al.
Publicado: (2020)

Social inheritance can explain the structure of animal social networks
por: Ilany, Amiyaal, et al.
Publicado: (2016)

Spatial stochastic modelling of the Hes1 gene regulatory network: intrinsic noise can explain heterogeneity in embryonic stem cell differentiation
por: Sturrock, Marc, et al.
Publicado: (2013)

Backup in gene regulatory networks explains differences between binding and knockout results
por: Gitter, Anthony, et al.
Publicado: (2009)

Novel Classes and Evolutionary Turnover of Histone H2B Variants in the Mammalian Germline
por: Raman, Pravrutha, et al.
Publicado: (2022)

Interference with the HNF4-dependent gene regulatory network diminishes ER stress in hepatocytes
por: Shah, Anit, et al.
Publicado: (2023)

Many, but not all, lineage-specific genes can be explained by homology detection failure
por: Weisman, Caroline M., et al.
Publicado: (2020)

RELATCH: relative optimality in metabolic networks explains robust metabolic and regulatory responses to perturbations
por: Kim, Joonhoon, et al.
Publicado: (2012)

A functional selection model explains evolutionary robustness despite plasticity in regulatory networks
por: Habib, Naomi, et al.
Publicado: (2012)

Networking Explained
por: Gallo, Michael, et al.
Publicado: (2001)

Can a single model explain both breast cancer and prostate cancer?
por: Friedman, A Edward
Publicado: (2007)

Stochastic events can explain sustained clustering and polarisation of opinions in social networks
por: Condie, Scott A., et al.
Publicado: (2021)

Can peer effects explain prescribing appropriateness? a social network analysis
por: Wang, Sophie Y., et al.
Publicado: (2023)

Stochastic fluctuations can reveal the feedback signs of gene regulatory networks at the single-molecule level
por: Jia, Chen, et al.
Publicado: (2017)

Response competition better explains Stroop interference than does response exclusion
por: Roelofs, Ardi
Publicado: (2020)

Interference with the HNF4-dependent gene regulatory network diminishes endoplasmic reticulum stress in hepatocytes
por: Shah, Anit, et al.
Publicado: (2023)

Can Selective MHC Downregulation Explain the Specificity and Genetic Diversity of NK Cell Receptors?
por: Carrillo-Bustamante, Paola, et al.
Publicado: (2015)

Can species‐specific prey responses to chemical cues explain prey susceptibility to predation?
por: Šmejkal, Marek, et al.
Publicado: (2018)

Single-plasmon interferences
por: Dheur, Marie-Christine, et al.
Publicado: (2016)

Estimating Sample-Specific Regulatory Networks
por: Kuijjer, Marieke Lydia, et al.
Publicado: (2019)

Recurrent neural networks can explain flexible trading of speed and accuracy in biological vision
por: Spoerer, Courtney J., et al.
Publicado: (2020)

A3SOM, abstained explainable semi-supervised neural network based on self-organizing map
por: Creux, Constance, et al.
Publicado: (2023)

Regulatory Network of Two Tumor-Suppressive Noncoding RNAs Interferes with the Growth and Metastasis of Renal Cell Carcinoma
por: Zhou, Hui, et al.
Publicado: (2019)

MSTN Regulatory Network in Mongolian Horse Muscle Satellite Cells Revealed with miRNA Interference Technologies
por: Budsuren, Undarmaa, et al.
Publicado: (2022)

Strength is in engagement: The rise of an online scientific community during the COVID‐19 pandemic
por: Cucinotta, Christine E, et al.
Publicado: (2021)

Commentary: “Can Selective MHC Downregulation Explain the Specificity and Genetic Diversity of NK Cell Receptors?”
por: Robert, Philippe A.
Publicado: (2015)

Qualitative Dynamical Modelling Can Formally Explain Mesoderm Specification and Predict Novel Developmental Phenotypes
por: Mbodj, Abibatou, et al.
Publicado: (2016)

Chemotherapy Can Interfere in Implantation in In-vitro Fertilization
por: Banker, Manish, et al.
Publicado: (2021)

Deciphering the autophagy regulatory network via single-cell transcriptome analysis reveals a requirement for autophagy homeostasis in spermatogenesis
por: Wang, Mei, et al.
Publicado: (2021)

Discovering Study-Specific Gene Regulatory Networks
por: Bo, Valeria, et al.
Publicado: (2014)

Predicting genotype-specific gene regulatory networks
por: Weighill, Deborah, et al.
Publicado: (2022)

The method to divide a sentence of requirement into individual requirements and the development of requirement specification editor which can describe individual requirements
por: Sato, Kuniya, et al.
Publicado: (2013)

Estimating the Relevance of World Disturbances to Explain Savings, Interference and Long-Term Motor Adaptation Effects
por: Berniker, Max, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_17vaoer9m1o5bti6172t7ab0e6