Long COVID manifests with T cell dysregulation, inflammation, and an uncoordinated adaptive immune response to SARS-CoV-2

Long COVID (LC), a type of post-acute sequelae of SARS-CoV-2 infection (PASC), occurs after at least 10% of SARS-CoV-2 infections, yet its etiology remains poorly understood. Here, we used multiple “omics” assays (CyTOF, RNAseq/scRNAseq, Olink) and serology to deeply characterize both global and SAR...

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Detalles Bibliográficos
Autores principales: Yin, Kailin, Peluso, Michael J., Luo, Xiaoyu, Thomas, Reuben, Shin, Min-Gyoung, Neidleman, Jason, Andrew, Alicer, Young, Kyrlia, Ma, Tongcui, Hoh, Rebecca, Anglin, Khamal, Huang, Beatrice, Argueta, Urania, Lopez, Monica, Valdivieso, Daisy, Asare, Kofi, Deveau, Tyler-Marie, Munter, Sadie E., Ibrahim, Rania, Ständker, Ludger, Lu, Scott, Goldberg, Sarah A., Lee, Sulggi A., Lynch, Kara L., Kelly, J. Daniel, Martin, Jeffrey N., Münch, Jan, Deeks, Steven G., Henrich, Timothy J., Roan, Nadia R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934605/
https://www.ncbi.nlm.nih.gov/pubmed/36798286
http://dx.doi.org/10.1101/2023.02.09.527892

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