Wnt activity reveals context-specific genetic effects on gene regulation in neural progenitors

Gene regulatory effects in bulk-post mortem brain tissues are undetected at many non-coding brain trait-associated loci. We hypothesized that context-specific genetic variant function during stimulation of a developmental signaling pathway would explain additional regulatory mechanisms. We measured...

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Detalles Bibliográficos
Autores principales: Matoba, Nana, Le, Brandon D, Valone, Jordan M, Wolter, Justin M, Mory, Jessica, Liang, Dan, Aygün, Nil, Broadaway, K Alaine, Bond, Marielle L, Mohlke, Karen L, Zylka, Mark J, Love, Michael I, Stein, Jason L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934631/
https://www.ncbi.nlm.nih.gov/pubmed/36798360
http://dx.doi.org/10.1101/2023.02.07.527357

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