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Scalable co-sequencing of RNA and DNA from individual nuclei

The ideal technology for directly investigating the relationship between genotype and phenotype would analyze both RNA and DNA genome-wide and with single-cell resolution. However, existing tools lack the throughput required for comprehensive analysis of complex tumors and tissues. We introduce a hi...

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Detalles Bibliográficos
Autores principales: Olsen, Timothy R., Talla, Pranay, Furnari, Julia, Bruce, Jeffrey N., Canoll, Peter, Zha, Shan, Sims, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934633/
https://www.ncbi.nlm.nih.gov/pubmed/36798358
http://dx.doi.org/10.1101/2023.02.09.527940