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Time to lysis determines phage sensitivity to a cytidine deaminase toxin/antitoxin bacterial defense system
Toxin-antitoxin (TA) systems are ubiquitous two-gene loci that bacteria use to regulate cellular processes such as phage defense. Here, we demonstrate the mechanism by which a novel type III TA system, avcID, is activated and confers resistance to phage infection. The toxin of the system (AvcD) is a...
Autores principales: | Hsueh, Brian Y., Sanath-Kumar, Ram, Bedore, Amber M., Waters, Christopher M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934689/ https://www.ncbi.nlm.nih.gov/pubmed/36798279 http://dx.doi.org/10.1101/2023.02.09.527960 |
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