Clinical testing of transcriptome-wide expression profiles in high-risk localized and metastatic prostate cancer starting androgen deprivation therapy: an ancillary study of the STAMPEDE abiraterone Phase 3 trial

Metastatic and high-risk localized prostate cancer respond to hormone therapy but outcomes vary. Following a pre-specified statistical plan, we used Cox models adjusted for clinical variables to test associations with survival of multi-gene expression-based classifiers from 781 patients randomized t...

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Detalles Bibliográficos
Autores principales: Parry, Marina A., Grist, Emily, Mendes, Larissa, Dutey-Magni, Peter, Sachdeva, Ashwin, Brawley, Christopher, Murphy, Laura, Proudfoot, James, Lall, Sharanpreet, Liu, Yang, Friedrich, Stefanie, Ismail, Mazlina, Hoyle, Alex, Ali, Adnan, Haran, Aine, Wingate, Anna, Zakka, Leila, Wetterskog, Daniel, Amos, Claire L., Atako, Nafisah B., Wang, Victoria, Rush, Hannah L., Jones, Robert J., Leung, Hing, Cross, William R., Gillessen, Silke, Parker, Chris C., Chowdhury, Simon, Lotan, Tamara, Marafioti, Teresa, Urbanucci, Alfonso, Schaeffer, Edward M., Spratt, Daniel E., Waugh, David, Powles, Thomas, Berney, Daniel M., Sydes, Matthew R., Parmar, Mahesh K.B., Hamid, Anis A., Feng, Felix Y., Sweeney, Christopher J., Davicioni, Elai, Clarke, Noel W., James, Nicholas D., Brown, Louise C., Attard, Gerhardt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934744/
https://www.ncbi.nlm.nih.gov/pubmed/36798177
http://dx.doi.org/10.21203/rs.3.rs-2488586/v1

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